RESUMO
Moral education is the internal requirement of the teaching reform in colleges and universities. The core is to tap the ideological and political education resources of different disciplines and professional courses, and establish an organic, uni?ed, full-disciplinary, all-round and full-function ideological and political education curriculum system; and judging from the inherent requirements of curriculum construction, curriculum is a carrier of ideological and political education, with a distinct education function and value orientation. English majors come into contact with western culture more in the learning process, and are susceptible to the in?uence of Western culture and ideas. As the core curriculum of English majors, English writing mostly focuses on the teaching of English writing skills, and lacks guidance on students' thought. This article starts from the three aspects of writing theme selection, class discussion and writing evaluation. It explores and practices moral education for English majors in English writing course, and re?ects on the implementation of moral education teaching in major courses for English majors in order to make students better educated morally
RESUMO
Abstract Objective: This study aimed to investigate the protective effects of baicalin on myocardial infarction in rats and explore the related mechanisms. Methods: Fifty Sprague Dawley rats were randomly divided into the control, model, and low-, medium- and high-dose baicalin groups. The latter 3 groups were intraperitoneally injected with baicalin, with a dose of 12.5, 25 and 50 mg/kg, respectively. Then, the myocardial infarction model was established. The hemodynamic of rats was tested, the serum lactate dehydrogenase (LDH), creatine kinase-MB (CK-MB), prostacyclin (PGI2) and thromboxane A2 (TXA2) were determined, the myocardial superoxide dismutase (SOD) and malondialdehyde (MDA) levels were detected, and the myocardial B-cell lymphoma-2 (Bcl-2) and Bcl-2 associated X (Bax) protein expressions were determined. Results: Compared with the model group, in the high-dose baicalin group the ST segment height and LVEDP were significantly decreased (P<0.05), the LVSP was significantly increased (P<0.05), the serum LDH, CK-MB and TXA2 levels were significantly decreased (P<0.05), the PGI2 level was significantly increased (P<0.05), the myocardial SOD level was significantly increased (P<0.05), and the myocardial MDA level was significantly decreased (P<0.05); the myocardial Bcl-2 protein level was significantly increased, and the Bax protein level was significantly decreased (P<0.05). Conclusion: Baicalin has protective effects on myocardial infarction in rats. The possible mechanisms may be related to its resistance to oxidative stress, and up-regulation of Bcl-2 protein expression and down-regulation of Bax protein expression in myocardial tissue.